Immunofluorescent Analysis of Testicular Biopsies with Germ Cell and Sertoli Cell Markers Shows Significant MVH Negative Germ Cell Depletion with Older Age at Orchiopexy
摘要：Undescended testis is the most common defect in male newborns. This condition is associated with increased risks of infertility and testicular malignancy due to abnormal germ cell development in the testes. Early surgery may limit such risks. We analyzed germ cell development vs age at orchiopexy using a germ cell marker and a Sertoli cell marker on testicular biopsies.
关键词：cryptorchidism; germ cells; orchiopexy; Sertoli cells; testis; AD-S adult dark spermatogonia; adult dark spermatogonia; AMH anti-Mullerian hormone; anti-Mullerian hormone; GC germ cell; germ cell; GCs/T germ cells per tubule; germ cells per tubule; MVH mouse VASA homologue; mouse VASA homologue; PLAP placental alkaline phosphatase; placental alkaline phosphatase; UDT undescended testes; undescended testes
论文方向：[{"id":13,"name":"细胞生物学"},{"id":896,"name":"医药科学"}]
发表期刊：The Journal of Urology Volume 191, Issue 2
发表时间：Fri Feb 28 00:00:00 CST 2014
数字识别码：10.1016/j.juro.2013.08.075
是否作者本人： 否
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