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An activating combination of CD2 antibodies stimulates tyrosine phosphorylation in a T lymphocyte cell line
作者:, Rebecca E. Thom
摘要:Abstract The activating combination of CD2 antibodies Leu-5b plus 9.1 stimulates tyrosine phosphorylation in the human T cell line Jurkat. The tyrosine phosphorylation has the same molecular weight pattern as that seen when cells are stimulated on the CD3 receptor with OKT3 antibodies. These data provide evidence that signal transduction by the CD2 receptor is coupled to an increase in tyrosine phosphorylation that is similar to that coupled to the CD3 receptor.
关键词:T cell; Tyrosine protein kinase; CD2 receptor; CD3 receptor
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发表期刊:FEBS Letters Volume 261, Issue 2
发表时间:Mon Feb 26 00:00:00 CST 1990
数字识别码:10.1016/0014-5793(90)80584-6
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