Pertussis toxin blocks angiotensin II-induced calcium influx but not inositol trisphosphate production in adrenal glomerulosa cell
摘要：Abstract Involvement of GTP-binding proteins in angiotensin II-induced mobilization of calcium has been examined in adrenal glomerulosa cells by using pertussis toxin. Pretreatment of glomerulosa cells with pertussis toxin abolishes angiotensin II-induced calcium influx without blocking inositol trisphosphate production. These results suggest a role of the pertussis toxin-sensitive GTP-binding protein in transducing angiotensin II-receptor occupancy into opening of calcium channel.
关键词：Angiotensin II(Adrenal glomerulosa cell)Ca2+ influxPertussis toxinInositol trisphosphate
论文方向：[{"id":13,"name":"细胞生物学"},{"id":879,"name":"生物化学"}]
发表期刊：FEBS Letters Volume 204, Issue 2
发表时间：Mon Aug 18 00:00:00 CDT 1986
数字识别码：10.1016/0014-5793(86)80841-9
是否作者本人： 否
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